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The Gut Brain Connection: How Stress Impacts Digestion

Published:

September 8, 2026

Written by:

Caitlyn Castiglione, MS, RDN

Medically Reviewed by:

Published:

September 9, 2026

From Our Dietitians
From Our Dietitians
Mind-Gut Connection
Mind-Gut Connection

The Gut-Brain Connection

Our gut and brain function is a bi-directional axis, similar to a two-way highway. A disturbance in the gut can impact our brain function by altering the absorption of nutrients that are essential to nervous system function and impairing the production and uptake of neurotransmitters. The opposite is true as well, a period of heightened stress at work, or stress on the body like an injury or surgery, can show up in the form of changes within the digestive system. The vagus nerve innervates our GI tract and is heavily impacted by stress responses. One of the major drivers of this connection is the autonomic nervous system. 

What Is the Autonomic Nervous System and How Does It Impact Digestion?

The autonomic nervous system is made up of two branches: sympathetic and parasympathetic. At the first signs of stress, the autonomic nervous system switches into sympathetic mode, otherwise known as fight-or-flight. In this state, adrenaline increases and the body gets ready to mount a response to the perceived threat. This looks like prioritizing circulation to the heart, lungs, and extremities rather than the digestive tract, and changes in transit time. 

This stress response can take place completely under your radar and can show up in your GI tract in the following ways:

  • Irregular bowel habits (constipation or diarrhea)
  • Bloating
  • Gas or abdominal discomfort
  • Changes in appetite
  • Increased sensitivity to digestive sensations

The parasympathetic side of the autonomic nervous system is more relaxed and is otherwise known as rest and digest. When the body is in a parasympathetic state, the body is better equipped to handle digestion, rest, and recovery. The vagus nerve often becomes more active in the parasympathetic state, supporting more normal digestive function. 

This is a rough idea of what happens during acute stress — things like having an argument, getting stuck in traffic, or anticipating giving a speech. During acute stress, symptoms may be minimal or go completely unnoticeable. 

On the other hand, long-term stressors leave less room for the nervous system to recover due to their persistent nature. In a lot of cases, periods of prolonged stress precede the emergence of GI issues. 

What You Can Do to Manage Stress

  1. Practice diaphragmatic breathing before meals. Diaphragmatic breathing signals safety and can help us enter the state of rest and digest. 
  2. Eat slowly and chew food thoroughly. Rushing during meals can signal stress, so it can be helpful to chew thoroughly to help activate the vagus nerve, promoting healthy digestion.
  3. Practice mindfulness during meals. Avoiding distractions like watching TV or having lunch in front of your computer can reduce stress while you’re actively eating. Finding a calm environment and eating slowly can reduce stressful inputs and improve how your food is digested.
  4. Find ways to manage overall stress. Participating in something you enjoy is a good first step in identifying stress management techniques. Common forms of stress management include prayer, meditation, physical activity, reading, art, and various activities that keep your hands busy. 

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Written by:

Caitlyn Castiglione, MS, RDN

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